Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCathepsin D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50373812(CHEMBL402305)Copy SMILESCopy InChI

Affinity DataIC50:  600nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50373812(CHEMBL402305)Copy SMILESCopy InChI

Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedMMDB
PDB3D Structure (crystal)
Copy BDB DOI

TargetBeta-secretase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50373812(CHEMBL402305)Copy SMILESCopy InChI

Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI