Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(CHEMBL253165 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human BACE in HEK293 cells by Swedish amyloid inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(CHEMBL253165 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  484nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(CHEMBL253165 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-...)
Affinity DataIC50:  4.88E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed