Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 4 hits in this display
Caspase-3(Homo sapiens (Human))Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
IC50: 2.90nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
Caspase-7(Homo sapiens (Human))Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
IC50: 9.70nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
Caspase-1(Homo sapiens (Human))Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
IC50: 9.97E+3nMAssay Description:Inhibition of human recombinant caspase 1 using Ac-YVAD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
Caspase-6(Homo sapiens (Human))Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
IC50: 7.89E+4nMAssay Description:Inhibition of human recombinant caspase 6 using Ac-VEID-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair