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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
24
hits in this display
Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 1.25nM
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 1.99nM
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Normandie Univ
Curated by
ChEMBL
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 9.30nM
Assay Description:
Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 mins
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 9.30nM
Assay Description:
Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assay
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Copy InChI
Affinity Data
Ki: 10nM
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Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 200nM
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Target
5-hydroxytryptamine receptor 3A
(RAT)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 398nM
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 501nM
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Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 794nM
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Target
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat))
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 1.26E+3nM
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Target
5-hydroxytryptamine receptor 3A
(RAT)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.26E+3nM
More data for this Ligand-Target Pair
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Target
Muscarinic acetylcholine receptor M2
(RAT)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 5.01E+3nM
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Target
Muscarinic acetylcholine receptor M1
(RAT)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
Ki: 6.31E+3nM
More data for this Ligand-Target Pair
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Target
D(2) dopamine receptor
(GUINEA PIG)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
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Affinity Data
Ki: >1.00E+4nM
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Target
Alpha-2B adrenergic receptor
(NEONATAL RAT)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
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Affinity Data
Ki: >1.00E+4nM
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Target
Alpha-2A adrenergic receptor [16-465]
(Rattus norvegicus (rat))
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
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Target Info
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Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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Target
Beta-2 adrenergic receptor
(Rattus norvegicus)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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Target
D(1A) dopamine receptor
(GUINEA PIG)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
IC50: 403nM
Assay Description:
Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured every 1 min for ...
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
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Affinity Data
IC50: 403nM
Assay Description:
Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
5-hydroxytryptamine receptor 4
(RAT)
Suven Life Sciences
Curated by
ChEMBL
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
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Affinity Data
EC50: 8.70nM
Assay Description:
Agonist activity at 5-HT4 receptor in Sprague-Dawley rat oesophagus assessed as relaxation of carbachol precontracted oesophagus
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Normandie Univ
Curated by
ChEMBL
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
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Affinity Data
EC50: 2nM
Assay Description:
Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Normandie Univ
Curated by
ChEMBL
Ligand
BDBM84950
(CAS_183782 | NSC_183782 | RS 67333)
Copy SMILES
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Affinity Data
EC50: 2nM
Assay Description:
In vitro inhibition of angiotensin I converting enzyme in rabbit lung with hippuryl-histidyl-leucine as substrate
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