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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
37
hits in this display
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.0100nM
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.0129nM
Assay Description:
Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligand
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.0300nM
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.0600nM
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.0700nM
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.100nM
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.100nM
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Target
5-hydroxytryptamine receptor 4
(Sus scrofa)
TBA
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.126nM
Assay Description:
Compound was evaluated for its ability to inhibit the binding of 5-HT4 receptor radioligand [125I]SB 207710 to piglet hippocampal membrane
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Target
5-hydroxytryptamine receptor 4
(RAT)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.310nM
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Target
5-hydroxytryptamine receptor 4
(RAT)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 0.390nM
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Target
5-hydroxytryptamine receptor 4
(RAT)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 1.25nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 126nM
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Université
Curated by
ChEMBL
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 158nM
Assay Description:
Binding affinity at 5HT3 receptor
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Target
5-hydroxytryptamine receptor 3A
(RAT)
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 398nM
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Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 1.00E+3nM
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Target
Adrenergic alpha2 receptor
(Mesocricetus auratus)
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 1.00E+3nM
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Target
Solute carrier family 22 member 1
(RAT)
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Ki: 1.00E+3nM
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 1.00E+3nM
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Target
D(1A) dopamine receptor
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 1.00E+3nM
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Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 1.00E+3nM
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: 1.00E+3nM
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Target
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: >1.00E+4nM
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Target
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: >1.00E+4nM
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Target
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: >1.00E+4nM
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Ki: >1.00E+4nM
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Ki: >1.00E+4nM
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Target
5-hydroxytryptamine receptor 1D
(GUINEA PIG)
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Ki: >1.00E+4nM
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Target
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
PDSP K
i
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Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Ki: >1.00E+4nM
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
IC50: 0.0794nM
Assay Description:
Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
IC50: 0.0800nM
Assay Description:
Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMP
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
IC50: 0.100nM
Assay Description:
Inhibition of 5-HT-evoked 5-HT4 receptor-mediated contractions in the guinea pig distal colon longitudinal muscle myenteric plexus (LMMP)
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Target
Thiosulfate sulfurtransferase
(Homo sapiens)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ...
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Target
60 kDa heat shock protein, mitochondrial
(Homo sapiens)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...
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Target
Co-chaperonin GroES
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...
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Target
Co-chaperonin GroES
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
IC50: >2.50E+5nM
Assay Description:
Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...
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Target
Chaperonin GroEL
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
IC50: >2.50E+5nM
Assay Description:
Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys...
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Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Affinity Data
Kd: 0.0200nM
Assay Description:
Binding affinity to 5HT4 receptor in guinea pig distal colon
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