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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Histone deacetylase 3
(Homo sapiens (Human))
Musc Foundation For Research Development
US Patent
Ligand
BDBM476606
(N-(4-(2-butylhydrazine-1- carbonyl)benzyl)benzamid...)
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Affinity Data
IC50: 8.56nM
Assay Description:
Recombinant HDACs 1, 2, and 3 (BPS Biosciences) were diluted to a concentration of 1 nM in HDAC buffer. 10 uL of this solution was added in 96-well f...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
Musc Foundation For Research Development
US Patent
Ligand
BDBM476606
(N-(4-(2-butylhydrazine-1- carbonyl)benzyl)benzamid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.60nM
Assay Description:
Allosteric inhibition of C-terminal His-tagged recombinant human HDAC3 expressed in Sf9 cells pre-incubated for 2 hrs before acetylated lysine-aminom...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
Musc Foundation For Research Development
US Patent
Ligand
BDBM476606
(N-(4-(2-butylhydrazine-1- carbonyl)benzyl)benzamid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18.9nM
Assay Description:
Recombinant HDACs 1, 2, and 3 (BPS Biosciences) were diluted to a concentration of 1 nM in HDAC buffer. 10 uL of this solution was added in 96-well f...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Musc Foundation For Research Development
US Patent
Ligand
BDBM476606
(N-(4-(2-butylhydrazine-1- carbonyl)benzyl)benzamid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 65.2nM
Assay Description:
Recombinant HDACs 1, 2, and 3 (BPS Biosciences) were diluted to a concentration of 1 nM in HDAC buffer. 10 uL of this solution was added in 96-well f...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
Musc Foundation For Research Development
US Patent
Ligand
BDBM476606
(N-(4-(2-butylhydrazine-1- carbonyl)benzyl)benzamid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 261nM
Assay Description:
Allosteric inhibition of HDAC3 in HEK293 cell lysates pre-incubated for 2 hrs before acetylated lysine-aminomethyl coumarin-BOC addition and measured...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI