Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 16 hits in this display
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
IC50: 45nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
IC50: 70nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
IC50: 190nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
IC50: 190nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
IC50: 490nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
IC50: 1.04E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
IC50: 1.04E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
BDBM163626(SR-3302 | US10807944, Compound RLS2-211 | US117319...)
IC50: 6.83E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair