Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 15 hits in this display
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
IC50: 230nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
IC50: 230nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
IC50: 720nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
IC50: 880nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
IC50: 880nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
IC50: 9.57E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
IC50: 1.31E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
BDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
IC50: >5.00E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair