Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 4 hits in this display
Caspase-3(Homo sapiens (Human))WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
BDBM50257248((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Caspase-3(Homo sapiens (Human))WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
BDBM50257248((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
IC50: 5.30nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
Caspase-7(Homo sapiens (Human))WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
BDBM50257248((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Caspase-7(Homo sapiens (Human))WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
BDBM50257248((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
IC50: 58nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair