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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Gsk
Ligand
BDBM27791
(2-{[2-({4-chloro-2-methoxy-5-[(1-propylpiperidin-4...)
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Affinity Data
IC50: 25nM
pH: 7.5 T: 2°C
Assay Description:
Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
G protein-coupled receptor kinase 5
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM27791
(2-{[2-({4-chloro-2-methoxy-5-[(1-propylpiperidin-4...)
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Affinity Data
IC50: 3.20E+3nM
Assay Description:
Displacement of BODIPY TR-ADP from GRK5 (unknown origin) preincubated for 10 mins followed by compound addition and measured after 10 to 15 mins by f...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Gsk
Ligand
BDBM27791
(2-{[2-({4-chloro-2-methoxy-5-[(1-propylpiperidin-4...)
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Affinity Data
IC50: 3.98E+3nM
Assay Description:
Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-adrenergic receptor kinase 1
(Homo sapiens (Human))
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM27791
(2-{[2-({4-chloro-2-methoxy-5-[(1-propylpiperidin-4...)
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Affinity Data
IC50: 6.30E+3nM
Assay Description:
Displacement of BODIPY TR-ADP from human GRK2 preincubated for 10 mins followed by compound addition and measured after 10 to 15 mins by fluorescence...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rhodopsin kinase GRK1
(Bos taurus)
University Of Michigan
Curated by
ChEMBL
Ligand
BDBM27791
(2-{[2-({4-chloro-2-methoxy-5-[(1-propylpiperidin-4...)
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Affinity Data
IC50: 1.30E+4nM
Assay Description:
Displacement of BODIPY TR-ADP from bovine GRK1 (1 to 535 residues) preincubated for 10 mins followed by compound addition and measured after 10 to 15...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI