Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50244812(CHEMBL4097113)
Affinity DataIC50:  12nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 co-expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50244812(CHEMBL4097113)
Affinity DataIC50:  53nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50244812(CHEMBL4097113)
Affinity DataIC50:  199nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC2 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50244812(CHEMBL4097113)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 2 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed