Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi:  48.7nM ΔG°:  -43.4kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi:  1.28E+3nM ΔG°:  -35.0kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi:  5.19E+3nM ΔG°:  -31.4kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi: >1.50E+4nM ΔG°: >-28.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed