Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent

LigandBDBM60566(2-(2-nitrophenoxy)-N''-[(4-oxidanylidenecyclohexa-...)Copy SMILESCopy InChI

Affinity DataIC50:  22nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay

LigandBDBM60566(2-(2-nitrophenoxy)-N''-[(4-oxidanylidenecyclohexa-...)Copy SMILESCopy InChI

Affinity DataEC50:  4.11E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI