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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
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Affinity Data
IC50: <250nM
Assay Description:
Inhibition of KDM5B (1 to 809 residues) (unknown origin) expressed in Escherichia coli using biotin-H3K4me3 as substrate preincubated for 10 mins fol...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
Copy InChI
Affinity Data
IC50: <250nM
Assay Description:
Inhibition of human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotinylated histone H3 as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 5C
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
Copy InChI
Affinity Data
IC50: <250nM
Assay Description:
Inhibition of recombinant human N-terminal FLAG-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected sf9 cells using biotin-H3K4me3 as...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
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Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of recombinant human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using methylated biotin-H3K9 substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 6A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of KDM6A (919 to 1401 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 6B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of human C-terminal FLAG-tagged KDM6B (1043 residues) expressed in baculovirus infected sf9 cells using H3K27me3 as substrate preincubated...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 3B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of recombinant KDM3B (842 to 1761 residues) (unknown origin) expressed in baculovirus infected sf9 cells using biotin-H3K9me as substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 3A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of recombinant human N-terminal FLAG-tagged KDM3A (2 to 1322 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me as ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 2B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 as...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4C
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158857
(CHEMBL3787547)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of KDM4C (1 to 349 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for 10...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI