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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
5-hydroxytryptamine receptor 3A
(GUINEA PIG)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 7.90nM
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
Medical College of Georgia
Curated by
PDSP K
i
Database
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 10.4nM
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Target
Sigma non-opioid intracellular receptor 1
(RAT)
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 11nM
Assay Description:
Tested for its binding affinity towards sigma-1 site in presence of [3H]- dextromethorphan
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Target
Sigma non-opioid intracellular receptor 1
(RAT)
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 11nM
Assay Description:
Tested for its binding affinity towards sigma-1 site in presence of [3H]- -(+)3 PPP
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
Medical College of Georgia
Curated by
PDSP K
i
Database
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 19.5nM
Assay Description:
Binding affinity against Sigma receptor type 1 was determined by the displacement of [3H]pentazocine radioligand
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Target
Sigma non-opioid intracellular receptor 1
(RAT)
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 32nM
Assay Description:
Tested for its binding affinity towards sigma-1 site in presence of [3H]- - (+) pentazocine
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Target
Sigma non-opioid intracellular receptor 1
(RAT)
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 41nM
Assay Description:
Tested for its binding affinity towards sigma-1 site in rat brain using E3H1-(+)-SKF 10047 as radioligand in rat brain
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Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Soochow University
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 76nM
Assay Description:
Binding affinity to muscarinic acetylcholine receptor M1 (unknown origin)
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Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Soochow University
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 76nM
Assay Description:
Binding affinity towards muscarinic m1 receptor
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
Medical College of Georgia
Curated by
PDSP K
i
Database
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 129nM
Assay Description:
Binding affinity to sigma-1 receptor (unknown origin)
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Target
5-hydroxytryptamine receptor 3A
(GUINEA PIG)
Syntex Discovery Research
Curated by
PDSP K
i
Database
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 165nM
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Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 167nM
Assay Description:
Binding affinity towards muscarinic m2 receptor
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Target
Sigma intracellular receptor 2
(Homo sapiens (Human))
Soochow University
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 1.95E+3nM
Assay Description:
Binding affinity to sigma-2 receptor (unknown origin)
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Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
Ki: 3.09E+3nM
Assay Description:
Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand
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Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.09E+3nM
Assay Description:
Binding affinity against dopamine transporter was determined by the displacement of [3H]WIN-35428 radioligand in rat brain
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Target
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
IC50: 32nM
Assay Description:
Inhibition of [3H]- (+) - pentazocine binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum
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Target
Solute carrier family 22 member 1
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
IC50: 1.55E+3nM
Assay Description:
Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of ASP+ after 2 mins by fluorescence assay
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Target
Perilipin-1
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
IC50: 1.87E+3nM
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Target
Perilipin-5
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
IC50: 2.03E+3nM
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Target
Hepatocyte nuclear factor 4-alpha
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM94507
(2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopenta...)
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Affinity Data
IC50: 1.09E+4nM
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