Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent

LigandBDBM558609(US11365196, Compound 102)Copy SMILESCopy InChI

Affinity DataIC50:  1.80nMAssay Description:The inhibitory activity of some compounds of the present disclosure against FGFR1, FGFR2, FGFR3, FGFR4, KDR was tested by mobility shift assay (conce...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent

LigandBDBM558609(US11365196, Compound 102)Copy SMILESCopy InChI

Affinity DataIC50:  4.10nMAssay Description:The inhibitory activity of some compounds of the present disclosure against FGFR1, FGFR2, FGFR3, FGFR4, KDR was tested by mobility shift assay (conce...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent

LigandBDBM558609(US11365196, Compound 102)Copy SMILESCopy InChI

Affinity DataIC50:  60nMAssay Description:The inhibitory activity of some compounds of the present disclosure against FGFR1, FGFR2, FGFR3, FGFR4, KDR was tested by mobility shift assay (conce...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI