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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences
US Patent
Ligand
BDBM556329
(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
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Affinity Data
IC50: 0.160nM
Assay Description:
Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cyclin-dependent kinase 6
(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences
US Patent
Ligand
BDBM556329
(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.72nM
Assay Description:
Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences
US Patent
Ligand
BDBM556329
(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 368nM
Assay Description:
Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cyclin-dependent kinase 5
(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences
US Patent
Ligand
BDBM556329
(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 705nM
Assay Description:
Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI