Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetBromodomain-containing protein 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50575643(CHEMBL4856289)Copy SMILESCopy InChI

Affinity DataIC50:  316nMAssay Description:Inhibition of 6His-Thr-BRD3 (1 to 435 residues) BD2 domain Y348A or Y73A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain testis-specific protein(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50575643(CHEMBL4856289)Copy SMILESCopy InChI

Affinity DataIC50:  398nMAssay Description:Inhibition of 6His-FLAG-Tev-BRDT (1 to 397 residues) BD2 domain Y309A or Y66A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50575643(CHEMBL4856289)Copy SMILESCopy InChI

Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of 6His-Thr-BRD2 (1 to 473 residues) BD2 domain Y386A or Y113A mutant (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain testis-specific protein(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50575643(CHEMBL4856289)Copy SMILESCopy InChI

Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of 6His-FLAG-Tev-BRDT (1 to 397 residues) BD1 domain (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50575643(CHEMBL4856289)Copy SMILESCopy InChI

Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50575643(CHEMBL4856289)Copy SMILESCopy InChI

Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of 6His-Thr-BRD2 (1 to 473 residues) BD1 domain (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBromodomain-containing protein 3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50575643(CHEMBL4856289)Copy SMILESCopy InChI

Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of 6His-Thr-BRD3 (1 to 435 residues) BD1 domain (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI