Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50231690(CHEMBL253060 | N-((2S,3R)-4-((S)-2,3-dihydro-1H-in...)Copy SMILESCopy InChI

Affinity DataIC50:  160nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50231690(CHEMBL253060 | N-((2S,3R)-4-((S)-2,3-dihydro-1H-in...)Copy SMILESCopy InChI

Affinity DataIC50:  3.72E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50231690(CHEMBL253060 | N-((2S,3R)-4-((S)-2,3-dihydro-1H-in...)Copy SMILESCopy InChI

Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI