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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50:  8nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >2.00E+5nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Italfarmaco

US Patent
LigandPNGBDBM618068(6-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: >2.00E+5nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent