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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 19 hits in this display   

TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  0.112nMAssay Description:Inhibition of human recombinant HDAC2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  0.119nMAssay Description:Inhibition of human recombinant HDAC2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  433nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  434nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant HDAC4 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human HDAC2 expressed in baculovirus expression system using fluorogenic peptide RHKK(Ac) as substrate by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human HDAC2 expressed in baculovirus expression system using fluorogenic peptide RHKK(Ac) as substrate by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant HDAC4 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC3/GST-tagged human Ncor2 (395 to 489 residues) expressed in baculovirus express...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using fluorogenic substrate by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic substrate by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculovirus expression system using fluorogenic substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus expression system using fluorogenic substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus expression system using fluorogenic subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus expression system using fluorogenic substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal FLAG-tagged/C-terminal His-tagged human HDAC1 using fluorogenic substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged/N-terminal GST-tagged human HDAC4 (627 to 1084 residues) expressed in baculovirus expression system u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC2 expressed in baculovirus expression system using fluorogenic substrate by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50494415(CHEMBL3086767)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC5 catalytic domain (656 to 1122 residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed