Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL

LigandBDBM50068988(CHEMBL3403475)Copy SMILESCopy InChI

Affinity DataKi:  48nMAssay Description:Inhibition of human factor 7a using H-D-Ile-Pro-Arg-pNA substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL

LigandBDBM50068988(CHEMBL3403475)Copy SMILESCopy InChI

Affinity DataKi:  560nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL

LigandBDBM50068988(CHEMBL3403475)Copy SMILESCopy InChI

Affinity DataKi:  580nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL

LigandBDBM50068988(CHEMBL3403475)Copy SMILESCopy InChI

Affinity DataKi:  790nMAssay Description:Inhibition of factor 2a (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI