Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Coagulation factor VII
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.350nM ΔG°: -53.4kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Coagulation factor VII
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.350nM
Assay Description:
Inhibition of human factor 7a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Vitamin K-dependent protein C
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 87nM ΔG°: -39.9kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasma kallikrein
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 114nM ΔG°: -39.2kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasminogen
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.20E+3nM ΔG°: -33.5kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >3.40E+3nM ΔG°: >-30.9kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >3.50E+3nM ΔG°: >-30.8kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.60E+3nM ΔG°: -30.8kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tissue-type plasminogen activator
(Homo sapiens (Human))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >3.90E+3nM ΔG°: >-30.6kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Bos taurus (bovine))
Genentech
Ligand
BDBM14714
((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.00E+3nM ΔG°: -30.5kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI