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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of recombinant N-terminal GST tagged PDE6C (unknown origin) expressed in baculovirus infected Sf9 cells using cGMP as substrate by malachi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)
Affinity DataIC50:  66nMAssay Description:Inhibition of full length recombinant human C-terminal His/Flag-tagged HDAC1 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)
Affinity DataIC50:  373nMAssay Description:Inhibition of full length recombinant human N-terminal GST tagged HDAC6 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)
Affinity DataIC50:  432nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)
Affinity DataIC50:  750nMAssay Description:Inhibition of recombinant PDE3A (unknown origin) expressed in baculovirus infected Sf9 cells using cAMP as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST tagged PDE9A2 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed