Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50424563(CHEMBL2312505)Copy SMILESCopy InChI

Affinity DataKi:  123nMAssay Description:Binding affinity to human GPR119 in HEK293FT cell membrane by radioligand binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50424563(CHEMBL2312505)Copy SMILESCopy InChI

Affinity DataEC50:  49nMAssay Description:Agonist activity at human GPR119 in HEK293 cells assessed as cAMP accumulation after 30 mins by CRE-beta-lactamase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI