Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310150((S)-2-amino-4-(2,6-diethylpyridin-4-yl)-4-(3-(2-fl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310150((S)-2-amino-4-(2,6-diethylpyridin-4-yl)-4-(3-(2-fl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310150((S)-2-amino-4-(2,6-diethylpyridin-4-yl)-4-(3-(2-fl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310150((S)-2-amino-4-(2,6-diethylpyridin-4-yl)-4-(3-(2-fl...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310150((S)-2-amino-4-(2,6-diethylpyridin-4-yl)-4-(3-(2-fl...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed