Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 6(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM425867(2-(4-ethylphenyl)-N-hydroxy- 1H-benzimidazole-6- c...)
Affinity DataIC50:  46nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM425867(2-(4-ethylphenyl)-N-hydroxy- 1H-benzimidazole-6- c...)
Affinity DataIC50:  46nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM425867(2-(4-ethylphenyl)-N-hydroxy- 1H-benzimidazole-6- c...)
Affinity DataIC50:  1.20E+3nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM425867(2-(4-ethylphenyl)-N-hydroxy- 1H-benzimidazole-6- c...)
Affinity DataIC50:  2.20E+3nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM425867(2-(4-ethylphenyl)-N-hydroxy- 1H-benzimidazole-6- c...)
Affinity DataIC50:  6.50E+3nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM425867(2-(4-ethylphenyl)-N-hydroxy- 1H-benzimidazole-6- c...)
Affinity DataIC50:  1.65E+5nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent