Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309889(2-(5-Ethyloxazolo[4,5-b]pyridin-2-yl)-2,5-diazabic...)
Affinity DataKi:  18.7nMAssay Description:Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309889(2-(5-Ethyloxazolo[4,5-b]pyridin-2-yl)-2,5-diazabic...)
Affinity DataKi: >5.26E+3nMAssay Description:Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309889(2-(5-Ethyloxazolo[4,5-b]pyridin-2-yl)-2,5-diazabic...)
Affinity DataIC50:  3.31E+3nMAssay Description:Agonist activity at human 5HT3 receptor expressed in human skin epithelial cells assessed as stimulation of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309889(2-(5-Ethyloxazolo[4,5-b]pyridin-2-yl)-2,5-diazabic...)
Affinity DataIC50:  2.77E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed