Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50:  44nMAssay Description:Inhibition of mouse DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50:  64nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of prostanoid IP receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CASP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of insulin receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of CASP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of EGF receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of D2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CB1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed