Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 20 hits in this display
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Ki: 13nM ΔG°: -45.0kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Ki: 15nM ΔG°: -44.7kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Ki: 16nM ΔG°: -44.5kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Ki: 21nM ΔG°: -43.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Ki: 44nM ΔG°: -42.0kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
IC50: 62nMAssay Description:Displacement of FAM-labeled ZBA248 from BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
IC50: 131nMAssay Description:Displacement of FAM-labeled ZBA248 from BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Kd: 19nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Kd: 18nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Kd: 24nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Kd: 34nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
BDBM50092341(CHEMBL3581660 | US9675697, Cpd. No. 22)
Kd: 40nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair