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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Eyes absent homolog 3
(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center
US Patent
Ligand
BDBM50209206
((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
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Affinity Data
IC50: 3.40E+3nM
Assay Description:
An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
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US Patent
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Target
Eyes absent homolog 3
(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center
US Patent
Ligand
BDBM50209206
((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
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Copy InChI
Affinity Data
IC50: 3.40E+3nM
Assay Description:
The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
PDB
Patents
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In Depth
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US Patent
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Target
Baculoviral IAP repeat-containing protein 5
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50209206
((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
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Affinity Data
Kd: 8.00E+3nM
Assay Description:
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PDB
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In Depth
Details
Article
PubMed
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