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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human))
Phasebio Pharmaceuticals
US Patent
Ligand
BDBM287662
(US10085984, Example 40 | US11040034, Ex. No. 40)
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Affinity Data
IC50: 50nM
Assay Description:
Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human))
Phasebio Pharmaceuticals
US Patent
Ligand
BDBM287662
(US10085984, Example 40 | US11040034, Ex. No. 40)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human))
Viamet Pharmaceuticals (Bermuda)
US Patent
Ligand
BDBM287662
(US10085984, Example 40 | US11040034, Ex. No. 40)
Copy SMILES
Copy InChI
Affinity Data
IC50: 750nM
Assay Description:
V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human))
Viamet Pharmaceuticals (Bermuda)
US Patent
Ligand
BDBM287662
(US10085984, Example 40 | US11040034, Ex. No. 40)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.50E+3nM
Assay Description:
Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI