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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50556867(CHEMBL4757224)
Affinity DataKd:  4.10E+3nMAssay Description:Inhibition of Nrf2 peptide (KKKKAFFAQLQLDEETGEFL) binding to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation const...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50556867(CHEMBL4757224)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to Keap1 Kelch domain (321 to 609 residues) (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50556867(CHEMBL4757224)
Affinity DataKd:  4.10E+3nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as dissociation constant by surface plasmon resonance based inhibition-in-solution ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50556867(CHEMBL4757224)
Affinity DataKd:  3.70E+3nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50556867(CHEMBL4757224)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to Keap1 Kelch domain (321 to 609 residues) (unknown origin) by SPR based direct binding assayMore data for this Ligand-Target Pair