Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 40 hits in this display
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
Ki: 255nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrateMore data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 33.5nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: <100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: <100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: <100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: <100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 201nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 240nMAssay Description:Inhibition of CDK7 (unknown origin) in human HAP1 cells incubated for 6 hrs by Western blot based competitive pull down assayMore data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 421nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrate in presence of Km ATPMore data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 550nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 550nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 550nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 550nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 550nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 550nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 550nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: 550nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: >1.00E+3nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: >1.00E+3nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: >1.00E+3nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: >1.00E+3nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
IC50: >1.00E+3nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrate in presence of 2 mM ATPMore data for this Ligand-Target Pair
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
BDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)