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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHistamine H4 receptor(Homo sapiens (Human))
The Centre For Addiction and Mental Health

Curated by PDSP Ki Database
LigandPNGBDBM50017656(CHEMBL1193 | Dimethyl-(3-phenyl-3-pyridin-2-yl-pro...)
Affinity DataKi:  4.18E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50017656(CHEMBL1193 | Dimethyl-(3-phenyl-3-pyridin-2-yl-pro...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50017656(CHEMBL1193 | Dimethyl-(3-phenyl-3-pyridin-2-yl-pro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50017656(CHEMBL1193 | Dimethyl-(3-phenyl-3-pyridin-2-yl-pro...)
Affinity DataEC50:  2.82E+4nMAssay Description:Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 5 ug/mlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed