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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Histamine H4 receptor
(Homo sapiens (Human))
The Centre For Addiction and Mental Health
Curated by
PDSP K
i
Database
Ligand
BDBM50017656
(CHEMBL1193 | Dimethyl-(3-phenyl-3-pyridin-2-yl-pro...)
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Affinity Data
Ki: 4.18E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Sodium channel protein type 1/2/3 subunit alpha
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017656
(CHEMBL1193 | Dimethyl-(3-phenyl-3-pyridin-2-yl-pro...)
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Affinity Data
IC50: 3.30E+4nM
Assay Description:
Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
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CHEMBL
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MCE
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PC sid
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In Depth
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PubMed
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Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50017656
(CHEMBL1193 | Dimethyl-(3-phenyl-3-pyridin-2-yl-pro...)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
DrugBank
MCE
KEGG
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In Depth
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Article
PubMed
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Target
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig))
Cairo University
Curated by
ChEMBL
Ligand
BDBM50017656
(CHEMBL1193 | Dimethyl-(3-phenyl-3-pyridin-2-yl-pro...)
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Affinity Data
EC50: 2.82E+4nM
Assay Description:
Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 5 ug/ml
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI