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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Protein kinase C delta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
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Affinity Data
Ki: 96nM
Assay Description:
Inhibition of PKCdelta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Protein kinase C delta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 96nM
Assay Description:
Inhibition of PKCdelta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C theta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.5nM
Assay Description:
Inhibition of PKCtheta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C theta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.5nM
Assay Description:
Inhibition of PKCtheta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C theta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.5nM
Assay Description:
Inhibition of human full length PKCtheta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 17nM
Assay Description:
Inhibition of PKCepsilon
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C delta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 26nM
Assay Description:
Inhibition of human full length PKCdelta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Inhibition of Lck
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Inhibition of Lck
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C eta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
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Affinity Data
IC50: 62nM
Assay Description:
Inhibition of PKCeta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C theta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 230nM
Assay Description:
Inhibition of PKCtheta in wild type T-cell assessed as blockade of anti CD3-stimulated IL2 production
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 520nM
Assay Description:
Inhibition of Lyn
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C theta type
(Mus musculus)
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
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Copy InChI
Affinity Data
IC50: 1.30E+3nM
Assay Description:
Inhibition of mouse PKCtheta in KO cells assessed as blockade of anti CD28-stimulated IL2 production
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C beta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
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Affinity Data
IC50: 1.60E+3nM
Assay Description:
Inhibition of PKCbeta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 2
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of MK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50239328
(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of AKT
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI