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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
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Affinity Data
IC50: 16nM
Assay Description:
Inhibition of full length human recombinant C-terminal His-tagged HDAC3/NcoR2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilo...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
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CHEMBL
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Target
Histone deacetylase 1
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
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Affinity Data
IC50: 96nM
Assay Description:
Inhibition of C-terminal FLAG/His-tagged recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Histone deacetylase 6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
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Affinity Data
IC50: 106nM
Assay Description:
Inhibition of N-terminal GST-tagged recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using Z-(Ac)Lys-AMC as substrate measu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Histone deacetylase 2
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
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Affinity Data
IC50: 146nM
Assay Description:
Compound was tested for the binding affinity towards Nicotinic acetylcholine receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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In Depth
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Article
PubMed
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Target
Histone deacetylase 1/2/3/6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
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Affinity Data
IC50: 370nM
Assay Description:
Inhibition of HDAC1/2/3/6 in human Cal27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition meas...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Histone deacetylase 1/2/3/6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
Copy SMILES
Copy InChI
Affinity Data
IC50: 490nM
Assay Description:
Inhibition of HDAC1/2/3/6 in human Cal27CisR cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1/2/3/6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
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Copy InChI
Affinity Data
IC50: 660nM
Assay Description:
Inhibition of HDAC1/2/3/6 in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition meas...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Histone deacetylase 1/2/3/6
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
Inhibition of HDAC1/2/3/6 in human A2780cisR cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by
ChEMBL
Ligand
BDBM50239822
(CHEMBL4080343)
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Affinity Data
IC50: 6.76E+3nM
Assay Description:
Inhibition of human recombinant HDAC8 expressed in Escherichia coli using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI