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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM92422
(CHEMBL407391 | PU09)
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Affinity Data
Ki: 1.43E+3nM
Assay Description:
Binding affinity to human GST tagged truncated LRRK2 G2019S mutant incubated for 2 hrs by TR-FRET based Lanthascreen kinase activity assay
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Target
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human))
Sandia National Laboratories
Curated by
ChEMBL
Ligand
BDBM92422
(CHEMBL407391 | PU09)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of human recombinant ZAP70 using EEEEYEEEE as substrate by ESI-MS analysis
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Target Info
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Target
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human))
Sandia National Laboratories
Curated by
ChEMBL
Ligand
BDBM92422
(CHEMBL407391 | PU09)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of human recombinant PYK2 by ESI-MS analysis
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Target
Phosphatidylinositol 4-kinase type 2-alpha
(Homo sapiens (Human))
Smith Kline & French Research
Curated by
ChEMBL
Ligand
BDBM92422
(CHEMBL407391 | PU09)
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Affinity Data
Ki: 1.50E+5nM
Assay Description:
Binding affinity (Ki) against human phosphatidylinositol 4-kinase
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Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM92422
(CHEMBL407391 | PU09)
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Copy InChI
Affinity Data
IC50: 3.36E+3nM
Assay Description:
Inhibition of recombinant human GST tagged truncated LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate in presence of ATP preincuba...
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Target Info
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University of Copenhagen
Ligand
BDBM92422
(CHEMBL407391 | PU09)
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Affinity Data
IC50: >1.00E+5nM
pH: 7.4 T: 2°C
Assay Description:
The screening of the compound library at the h5-HT3A-HEK293 cell line and the subsequent functional characterization of the compounds were performed ...
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Target
Phosphatidylinositol 4-kinase type 2-alpha
(Homo sapiens (Human))
Smith Kline & French Research
Curated by
ChEMBL
Ligand
BDBM92422
(CHEMBL407391 | PU09)
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Affinity Data
IC50: 2.18E+5nM
Assay Description:
Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding site
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Target
Heat shock protein HSP 90-alpha/90-beta
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM92422
(CHEMBL407391 | PU09)
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Affinity Data
IC50: 1.50E+6nM
Assay Description:
Inhibition of HSP90 (unknown origin) by confocal fluorescence-based biochemical assay
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PDB
3D Structure (crystal)
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