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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
G-protein coupled bile acid receptor 1
(Mus musculus)
Ardelyx
Curated by
ChEMBL
Ligand
BDBM50459136
(CHEMBL4204655)
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Affinity Data
EC50: 2nM
Assay Description:
Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
G-protein coupled bile acid receptor 1
(Homo sapiens (Human))
Ardelyx
Curated by
ChEMBL
Ligand
BDBM50459136
(CHEMBL4204655)
Copy SMILES
Copy InChI
Affinity Data
EC50: 25nM
Assay Description:
Agonist activity at human TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI