Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL

LigandBDBM304985(3-{4-chloro-3-[(N-methyl-1,5-dimethyl-1H-pyrazole-...)Copy SMILESCopy InChI

Affinity DataIC50:  320nMAssay Description:Displacement of 5'-TAMRA-labelled NRF2 peptide from human N-terminal His6-tagged KEAP1 Kelch domain (321 to 609 residues) expressed in baculovirus in...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetKelch-like ECH-associated protein 1 [321-609](Homo sapiens (Human))
Glaxosmithkline

US Patent

LigandBDBM304985(3-{4-chloro-3-[(N-methyl-1,5-dimethyl-1H-pyrazole-...)Copy SMILESCopy InChI

Affinity DataIC50:  550nMAssay Description:10-point semi-log dilution curves in DMSO are prepared in 96-well polypropylene plates to 100× final assay concentration. Compound curves are then di...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI