Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
Caspase-3(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)Caspase-7(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Ki: 190nM ΔG°: -38.4kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-8(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Ki: 4.00E+3nM ΔG°: -30.8kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-1(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Ki: 1.20E+4nM ΔG°: -28.1kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-6(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Ki: 2.20E+4nM ΔG°: -26.6kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-2(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Ki: 3.00E+4nM ΔG°: -25.8kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-4(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Ki: 9.60E+4nM ΔG°: -22.9kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-5(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Ki: 9.80E+4nM ΔG°: -22.9kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair