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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  22nMAssay Description:Inhibition of VEGFR-1 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  37nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  46nMAssay Description:Inhibition of VEGFR-3 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  88nMAssay Description:Inhibition of PDGFRbeta (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  125nMAssay Description:Inhibition of C-kit (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  192nMAssay Description:Inhibition of FGFR1 (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  351nMAssay Description:Inhibition of C-fms (unknown origin) after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  430nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  590nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  910nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50457640(CHEMBL4213341)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using fluorogenic Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed