Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246140(CHEMBL513744 | D3RKN_5 | N-methyl-N-(3-((2-(2-oxoi...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of GST-tagged FAK (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246140(CHEMBL513744 | D3RKN_5 | N-methyl-N-(3-((2-(2-oxoi...)
Affinity DataIC50:  190nMAssay Description:Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50246140(CHEMBL513744 | D3RKN_5 | N-methyl-N-(3-((2-(2-oxoi...)
Affinity DataKd:  20nMAssay Description:D3R2022More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50246140(CHEMBL513744 | D3RKN_5 | N-methyl-N-(3-((2-(2-oxoi...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50246140(CHEMBL513744 | D3RKN_5 | N-methyl-N-(3-((2-(2-oxoi...)
Affinity DataKd:  2.90E+3nMAssay Description:D3R2021More data for this Ligand-Target Pair
In DepthDetails PubMed