Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273673((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)pr...)
Affinity DataKi:  1.20nMAssay Description:Displacement of fluorescently tagged SM5F from human cIAP-1 BIR3 expressed in Escherichia coli BL21 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 8(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273673((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)pr...)
Affinity DataKi:  4.60nMAssay Description:Displacement of fluorescently tagged SM5F from human cIAP-2 BIR3 expressed in Escherichia coli BL21 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273673((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)pr...)
Affinity DataEC50:  1.80E+4nMAssay Description:Antagonist activity at XIAP linker BIR2-BIR3 domain assessed as induction of caspase-9 activity using Z-LEHD as substrate preincubated for 15 mins me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50273673((5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)pr...)
Affinity DataEC50:  9.28E+3nMAssay Description:Antagonist activity at XIAP linker BIR2-BIR3 domain assessed as induction of caspase-3 activity using Ac-DEVD-AFC as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed