Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandBDBM26397(2,4-diamino-5,6-disubstituted pyrimidine, 11 | 6-[...)Copy SMILESCopy InChI

Affinity DataKi:  3.5nM ΔG°:  -48.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

LigandBDBM26397(2,4-diamino-5,6-disubstituted pyrimidine, 11 | 6-[...)Copy SMILESCopy InChI

Affinity DataKi:  5.10nM ΔG°:  -47.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI