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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Beta-secretase 2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM244051
(US9428476, 4b)
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Affinity Data
Ki: 1nM ΔG°: -52.2kJ/mole
pH: 5.0 T: 2°C
Assay Description:
BACE-mediated hydrolysis of this peptide results in an increase in relative fluorescence (RFU) at 620 nm after excitation with 320 nm light Inhibitor...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM244051
(US9428476, 4b)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2nM ΔG°: -50.5kJ/mole
pH: 5.0 T: 2°C
Assay Description:
This assay monitors the increase of 620 nm fluorescence that resulted from BACE1 cleavage of an APPswedish APPswe mutant peptide FRET substrate (QSY7...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI