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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetAcetylcholine-binding protein(Lymnaea stagnalis)
University of California San Diego

LigandPNGBDBM91624(alpha7 agonists 4t)
Affinity DataKi:  1.30nM ΔG°:  -49.9kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSoluble acetylcholine receptor(Aplysia Californica)
University of California San Diego

LigandPNGBDBM91624(alpha7 agonists 4t)
Affinity DataKi:  16nM ΔG°:  -43.8kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSoluble acetylcholine receptor(Aplysia Californica)
University of California San Diego

LigandPNGBDBM91624(alpha7 agonists 4t)
Affinity DataKi:  109nM ΔG°:  -39.1kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSoluble acetylcholine receptor(Aplysia Californica)
University of California San Diego

LigandPNGBDBM91624(alpha7 agonists 4t)
Affinity DataKi:  600nM ΔG°:  -34.9kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of California San Diego

LigandPNGBDBM91624(alpha7 agonists 4t)
Affinity DataKi:  1.40E+4nM ΔG°:  -28.8kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
University of California San Diego

LigandPNGBDBM91624(alpha7 agonists 4t)
Affinity DataKi:  1.50E+4nM ΔG°:  -28.6kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California San Diego

LigandPNGBDBM91624(alpha7 agonists 4t)
Affinity DataEC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed