Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 13 hits in this display
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
Ki: 949nMpH: 5.0Assay Description:This assay monitored the increase of 620 nm fluorescence that resulted from BACE1 cleavage of an APPswedish APPswe mutant peptide FRET substrate (QSY...More data for this Ligand-Target Pair
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
IC50: <2.20nMAssay Description:Inhibition of human BACE1 using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon green]KK-OH as substrate after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
IC50: 4.5nMAssay Description:Inhibition of human BACE2 using biotin-GLTNIKTEEISEISYEVEFR-C[Oregon green]KK-OH as substrate after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
BDBM143218(US8940748, 34 | US9029362, 34 | US9687494, 34)
IC50: >1.00E+6nMAssay Description:Inhibition of human Cathepsin D using Mca-Gly-Lys-Pro-Ile-Leu-Phe-PheArg-Leu-Lys(Dnp)-D-Arg-NH2 as substrate after 45 minsMore data for this Ligand-Target Pair