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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Beta-secretase 2
(Homo sapiens (Human))
TBA
US Patent
Ligand
BDBM276786
(3-chloro-N-{4-fluoro-3-[(5R)-3-imino-2,5-dimethyl-...)
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Affinity Data
Ki: 0.220nM
pH: 5.0
Assay Description:
Inhibitor IC50s, at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Beta-secretase 1
(Homo sapiens (Human))
TBA
US Patent
Ligand
BDBM276786
(3-chloro-N-{4-fluoro-3-[(5R)-3-imino-2,5-dimethyl-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.20nM
pH: 5.0
Assay Description:
The following reagents were used in this assay. Na+-Acetate pH 5.0; 1% Brij-35; Glycerol; Dimethyl Sulfoxide (DMSO); Recombinant human soluble BACE-1...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI