Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50036582(CHEMBL3354255)Copy SMILESCopy InChI

Affinity DataKi:  16nMAssay Description:Inhibition of purified human BACE1 by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50036582(CHEMBL3354255)Copy SMILESCopy InChI

Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of cathepsin-D (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI